structure determination
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About structure determination

Our understanding of life at the molecular level is highly dependent on the ability to map the molecular details of individual proteins and nucleic acids as well as their interactions with each other and with small molecules (inhibitors, cofactors, substrates, etc.). The determination of 3-D structures of proteins is crucial for the understanding of these interactions as well as their structure–function relationships, which also has many practical applications in drug design and protein engineering.

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