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About screening antibodies

We have done a large number of whole-cell based phage display library screening projects to select internalizing antibodies and peptides specific for various cell surface receptors such as EGFR, NTRK2, CTLA4, HER2, CD20, CD3, CD59, transferrin receptor, and CD33. Our staff scientists also have extensive experience in the discovery of novel marker receptors by selecting internalizing antibodies and peptides that are specific for certain cell types. Methodologies are developed to reduce the number of internalizing phage particles that do not target receptor-specific to exclude phage particles which are merely bound to the cell surface and to selectively identify phage particles that are capable of crosslinking receptors rather than merely binding.

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