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About lentivirus particle

Lentiviruses are a subset of retroviruses, with the ability to intergrate into host chromosomes, and to infect both dividing and non-dividing cells. They are excellent tools which used to deliver gene expression or knockdown. Several features make lentivirus gene delivery system preferable. Letiviral vectors can integrate transgenes into the host genomic DNA but do not transfer sequences that encode for proteins derived from the packaging virus. Finally, lentiviral vectors can infect a broad range of cell lines or model organisms (mouses, rat, etc).

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