Histone Demethylase Screening
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About Histone Demethylase Screening

HDMTs are found to be vital in cell development and differentiation. In addition, they are shown to participate in the regulation of chromatin remodeling, cell death, and global DNA methylation. Furthermore, HDMTs are also involved in some pathological processes such as cancer and inflammatory diseases. It is important to detect activity and inhibition of HDMTs in clarifying mechanisms of epigenetic regulation of gene activation and silencing, which has potential in benefiting cancer therapeutics.

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